Article
Why different rules are required for polygenic inheritance: lessons from studies of the DRD2 gene.
Alcohol (Fayetteville, N.Y.) - 1 Jul 1998
Comings D E
Abstract excerpt
In 1990 Blum, Noble and coworkers reported a significant association between the 1 allele of the Tarq1A polymorphism of the D2 dopamine receptor gene (DRD2) and severe alcoholism. Subsequently, some reports using both linkage and association techniques supported this finding whereas others either...
Topics
- Alcoholism
- Alleles
- Gene Frequency
- Genetic Linkage
- Haplotypes
- Humans
- Hybrid Vigor
- Mutation
- Pedigree
- Receptors, Dopamine D2