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Article

Mutations and modifications support a 'pitted-flexiball' model for alpha-crystallin.

International journal of biological macromolecules - 1 Jan 2000

Smulders R H, van Boekel M A, de Jong W W

Abstract excerpt

alpha-Crystallin is renown for resisting crystallization and electron microscopic image analysis. The spatial conformation thus remaining elusive, the authors explored the structure and chaperone functioning by analyzing the effects of site-directed mutagenesis, the properties of naturally occurring aberrant forms of alpha-crystallin and the influence of chemical modifications. The authors observed that the...

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PMID: 9650073
DOI: 10.1016/s0141-8130(98)00016-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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