Article
The rapid detection of the quantity (genotype) and cell lineage (immunophenotype) of contaminating maternal white cells in cord blood samples by fluorescence in situ hybridization combined with confocal laser scanning microscopy.
Blood cells - 1 Jan 1994
Wernet P, Kögler G, Somville T
Abstract excerpt
The role of maternal blood cell contamination in cord blood as hematopoietic stem cell transplant could be an important factor driving the graft vs. host reactivity. Therefore, the efficiacy of fluorescence-labeled chromosome probes for the X and Y chromosomes to study contaminating maternal cell...
Topics
- Antigens, CD
- Colony-Forming Units Assay
- Female
- Fetal Blood
- Genotype
- Humans
- Immunophenotyping
- In Situ Hybridization, Fluorescence
- Infant, Newborn
- Interphase
- Leukocyte Count
- Male
- Maternal-Fetal Exchange
- Microscopy, Confocal
- Pregnancy
- Sensitivity and Specificity
- X Chromosome
- Y Chromosome