Article
Oncogenes as regulators of apoptosis.
Essays in biochemistry - 1 Jan 2003
Labazi Mohamed, Phillips Andrew C
Abstract excerpt
Although cancer is a disease that will afflict one out of three people in the Western world, when considered at a cellular level, it is a rare clonal event. Long-lived organisms, such as humans, have evolved strategies to restrict the development of potentially malignant cells, and one such mechanism is the coupling of proliferative and apoptotic pathways. Multiple oncogenes have the ability to trigger apoptosis...
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