Article
Approaches and issues in defining asthma and associated phenotypes map to chromosome susceptibility areas in large Minnesota families. The Collaborative Study for the Genetics of Asthma (CSGA).
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Apr 1998
Blumenthal M N, Rich S S, King R, Weber J
Abstract excerpt
Evidence for linkage of asthma and its associated phenotypes with susceptibility genes on chromosome 12 has been demonstrated in one group of Minnesota families. The evidence is strong in affected sib pairs and weakens in analysis of the large pedigrees. A second group of families provided little...
Topics
- Adolescent
- Adult
- Age of Onset
- Asthma
- Bronchial Hyperreactivity
- Chromosome Mapping
- Chromosomes, Human, Pair 12
- Family Health
- Female
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Hypersensitivity, Immediate
- Immunoglobulin E
