Article
Detection of thalassemia genes using smeared blood film or leukocytes adhering to polysthylene fibers.
The Southeast Asian journal of tropical medicine and public health - 1 Jan 1997
Tatsumi N, Yokota M, Shindoh K, Funahara Y, Nathalang O, Sukpanichnant S, Bunyaratvej A, Fucharoen S
Abstract excerpt
Presently genetic analyses for thalassemia types require relatively large amounts of heparinized blood (5 to 10 ml), and transport as well as degeneration of these sample is a problem in the developing world. We have developed a new method to simplify this procedure and obtain DNAs from small spe...
Topics
- DNA
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Humans
- Leukocytes
- Mutation
- Polyesters
- Polymerase Chain Reaction
- Thalassemia