Nucleotide excision repair is not required for the antiapoptotic function of insulin-like growth factor 1.

doi:10.1006/excr.1998.4087

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Article

Nucleotide excision repair is not required for the antiapoptotic function of insulin-like growth factor 1.

Experimental cell research - 15 Jun 1998

Lee-Kwon W, Park D, Bernier M

Abstract excerpt

The expression of ERCC1, a member of the nucleotide excision repair (NER) family, is enhanced in cells transfected with insulin-like growth factor 1 (IGF-1) receptors. Of interest, an excellent concordance between ERCC1 expression and NER-mediated cell survival has been demonstrated. The two aims...

Topics

Animals
Apoptosis
CHO Cells
Cricetinae
DNA Repair
DNA-Binding Proteins
Endonucleases
Gene Expression Regulation
Humans
Insulin-Like Growth Factor I
Mutation
Proteins
Receptor, IGF Type 1
Signal Transduction

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