Article
Nucleotide excision repair is not required for the antiapoptotic function of insulin-like growth factor 1.
Experimental cell research - 15 Jun 1998
Lee-Kwon W, Park D, Bernier M
Abstract excerpt
The expression of ERCC1, a member of the nucleotide excision repair (NER) family, is enhanced in cells transfected with insulin-like growth factor 1 (IGF-1) receptors. Of interest, an excellent concordance between ERCC1 expression and NER-mediated cell survival has been demonstrated. The two aims of the present study were to determine the signaling pathways used by IGF-1 to confer protection against apoptotic...
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