Article
Cutting Edge: Antigen-Dependent Regulation of Telomerase Activity in Murine T Cells
1 Jun 1998
Abstract excerpt
Telomeres, structures on the ends of linear chromosomes, function to maintain chromosomal integrity. Telomere shortening occurs with cell division and provides a mechanism for limiting the replicative potential of normal human somatic cells. Telomerase, a ribonucleoprotein enzyme, synthesizes telomeric repeats on chromosomal termini, potentially extending the capacity for cell division. The present study...
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