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Article

Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging

1 Dec 1997

Abstract excerpt

Telomerase activity and the regulation of telomere length are factors which have been implicated in the control of cellular replication. These variables have been examined during human lymphocyte development, differentiation, activation, and aging. It was found that telomere length of peripheral blood CD4+ T cells decreases with age as well as with differentiation from naive to memory cells in vivo, and decreases...

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PMID: 9476664
DOI: 10.1111/j.1600-065x.1997.tb01026.x

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