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Article

The Maintenance of Telomere Length in CD28+ T Cells During T Lymphocyte Stimulation

24 Jul 2017

Abstract excerpt

Telomerase activity is not readily detected in resting human T lymphocytes, however upon antigen presentation, telomerase is transiently upregulated. Presently, it is not known if telomerase activation is necessary for the proliferation of T cells or for the maintenance of telomere lengths. In this study, we found that telomerase activation is not required for the short- term proliferation of T cells and that...

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PMID: 28754961
DOI: 10.1038/s41598-017-05174-7

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