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Article

KH domain integrity is required for wild-type localization of Sam68.

Experimental cell research - 25 May 1998

McBride A E, Taylor S J, Shalloway D, Kirkegaard K

Abstract excerpt

The protein Sam68 (Src-associated in mitosis, 68 kDa) has been found to bind to SH2 and to SH3 domain-containing proteins and to RNA. Although its protein-protein interactions implicate Sam68 in cell signaling, the significance of its RNA binding remains obscure. In most cells, Sam68 shows diffus...

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Identifiers

PMID: 9633516
DOI: 10.1006/excr.1998.4047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9633516-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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KH domain integrity is required for wild-type localization of Sam68.PMID 9633516Read ↗

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Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev.Semantic proximity Read ↗

Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activationSemantic proximity Read ↗

The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor.Semantic proximity Read ↗

Expression of Sam68 Associates with Neuronal Apoptosis and Reactive Astrocytes After Spinal Cord Injury.Semantic proximity Read ↗

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