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Article

High expression of Sam68 contributes to metastasis by regulating vimentin expression and a motile phenotype in oral squamous cell carcinoma.

Oncology reports - 1 Oct 2022

Komiyama Takuya, Kuroshima Takeshi, Sugasawa Takehito, Fujita Shin-Ichiro, Ikami Yuta, Hirai Hideaki, Tsushima Fumihiko, Michi Yasuyuki, Kayamori Kou, Higashino Fumihiro, Harada Hiroyuki

Abstract excerpt

The present study aimed to investigate the clinical and biological significance of Src‑associated in mitosis 68 kDa (Sam68) in oral squamous cell carcinoma (OSCC). Immunohistochemical analysis was performed on tissue samples obtained from 77 patients with OSCC. Univariate analysis revealed that the high expression of Sam68 was significantly correlated with advanced pathological T stage (P=0.01), positive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36082807
DOI: 10.3892/or.2022.8398
PMCID: PMC9478953

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