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Article

Complement contributes to the rejection of complete and class I major histocompatibility complex--incompatible cardiac allografts.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 May 1998

Qian Z, Jakobs F M, Pfaff-Amesse T, Sanfilippo F, Baldwin W M

Abstract excerpt

BACKGROUND: We have demonstrated previously that the terminal complement component C6 contributes to the acute rejection of ACI cardiac allografts by PVG recipients. ACI rats differ from PVG rats at major and minor histocompatibility antigens and ACI cardiac allografts stimulate vigorous alloantibody responses in PVG rats. We have now bred the C6 deficiency onto four PVG congenic rat strains to determine the...

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Identifiers

PMID: 9628565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Complement contributes to the rejection of complete and class I major histocompatibility complex--incompatible cardiac allografts.PMID 9628565Read ↗

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