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Article

Complement regulation in the GalT KO era

1 Jan 2010

Abstract excerpt

A number of institutes have reported on the successful production of alpha-galactosyltransferase knockout (GalT-KO) pigs. After producing such pigs, hyperacute rejection appeared to no longer be a problem. However, acute vascular rejection (AVR)/acute humoral xenograft rejection (AHXR) is defined as a rejection that begins within 24 h after transplantation and gradually destroys the graft. The origin of AVR/AHXR...

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PMID: 20149185
DOI: 10.1111/j.1399-3089.2010.00569.x

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