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Article

Association Between ACE (I/D) Polymorphism and Essential Hypertension (EH): An Updated Systematic Review and Meta-Analysis.

International journal of environmental research and public health - 20 Mar 2026

Smallwood Athina, Akam Elizabeth, Hunter David John, Singh Monica, Singh Puneetpal, Mastana Sarabjit

Abstract excerpt

BACKGROUND: Essential hypertension (EH) refers to elevated arterial blood pressure with unknown etiology, which becomes more prevalent with age. Although the D allele of the ACE (I/D) polymorphism has been linked to EH, this association is not consistent across global populations. This systematic review and meta-analysis examined the relationship between the ACE (I/D) polymorphism and EH in diverse populations to...

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Identifiers

PMID: 41899774
DOI: 10.3390/ijerph23030397
PMCID: PMC13027306

Genes

ACE

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