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Article

aly/aly mice: a unique model of biliary disease.

Hepatology (Baltimore, Md.) - 1 Jun 1998

Tsuneyama K, Kono N, Hoso M, Sugahara H, Yoshida K, Katayanagi K, Gershwin M E, Saito K, Nakanuma Y

Abstract excerpt

An autosomal recessive murine mutation, coined "aly/aly" or "alymphoplasia," was recently reported. Homozygotes for aly are defective in both humoral and cell-mediated immune function and have diffuse lymphoid cell infiltration of various tissues, particularly around the conduit ducts of the panc...

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Identifiers

PMID: 9620319
DOI: 10.1002/hep.510270606

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9620319-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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aly/aly mice: a unique model of biliary disease.PMID 9620319Read ↗

A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice.Semantic proximity Read ↗

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Prenatal determination of obesity, tumor susceptibility, and coat color pattern in viable yellow (Avy/a) mice. The yellow mouse syndrome.Semantic proximity Read ↗

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The alymphoplasia (aly) mutation co-segregates with the intercellular adhesion molecule-2 (lcam-2) on mouse chromosome 11.Semantic proximity Read ↗

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype.Semantic proximity Read ↗

Mouse models of Hermansky Pudlak syndrome: a review.Semantic proximity Read ↗

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