Article
The alymphoplasia (aly) mutation co-segregates with the intercellular adhesion molecule-2 (lcam-2) on mouse chromosome 11.
International immunology - 1 Jul 1994
Kuramoto T, Mashimo T, Koike R, Miyawaki S, Yamada J, Miyasaka M, Serikawa T
Abstract excerpt
A new spontaneous autosomal recessive mutation alymphoplasia (aly), which causes a systemic defect of lymph nodes and Peyer's patches, was mapped on mouse chromosome 11 by linkage analysis using (ALY x MSM)F1 x ALY backcross progeny (155 mice). The gene order and map distances on the chromosome w...
Topics
- Animals
- Antigens, CD
- Base Sequence
- Cell Adhesion Molecules
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- DNA Mutational Analysis
- Genetic Linkage
- Humans
- Immunoenzyme Techniques
- Lymph Nodes
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Molecular Sequence Data
- Mutation
- Peyer's Patches
- RNA, Messenger