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Article

Genetic analysis of male pattern baldness and the 5alpha-reductase genes.

The Journal of investigative dermatology - 1 Jun 1998

Ellis J A, Stebbing M, Harrap S B

Abstract excerpt

Genetic predisposition and androgen dependence are important characteristics of the common patterned loss of scalp hair known as male pattern baldness. The involvement of the 5alpha-reductase enzyme in male pattern baldness has been postulated due to its role in the metabolism of testosterone to dihydrotestosterone. There are two known isozymes of 5alpha-reductase. Type I has been predominantly localized to the...

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PMID: 9620288
DOI: 10.1046/j.1523-1747.1998.00224.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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