Article
Transcription of INO2 and INO4 is regulated by the state of protein N-myristoylation in Saccharomyces cerevisiae.
Nucleic acids research - 15 Jun 1998
Cok S J, Martin C G, Gordon J I
Abstract excerpt
Inositol regulates transcription of Saccharomyces cerevisiae genes required for de novo synthesis of acylCoAs and phospholipids. Removal of inositol results in transcriptional activation by heterodimeric complexes of two bHLH proteins, Ino2p and Ino4p. In the presence of inositol, transcription i...
Topics
- Acyltransferases
- Basic Helix-Loop-Helix Transcription Factors
- DNA-Binding Proteins
- Fatty Acid Synthases
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Inositol
- Mutation
- Myristic Acid
- Promoter Regions, Genetic
- RNA, Fungal
- RNA, Messenger
- Recombinant Fusion Proteins
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Trans-Activators
- Transcription Factors