Modulation of tubulin polypeptide ratios by the yeast protein Pac10p.

doi:10.1093/genetics/149.2.857

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Article

Modulation of tubulin polypeptide ratios by the yeast protein Pac10p.

Genetics - 1 Jun 1998

Alvarez P, Smith A, Fleming J, Solomon F

Abstract excerpt

Normal assembly and function of microtubules require maintenance of the proper levels of several proteins, including the tubulin polypeptides themselves. For example, in yeast a significant excess of beta-tubulin causes rapid microtubule disassembly and subsequent cell death. Even the modest exce...

Topics

Cloning, Molecular
Endoribonucleases
Fungal Proteins
Gene Deletion
Genes, Fungal
Genes, Lethal
Kinesins
Microtubule-Associated Proteins
Microtubules
Mutagenesis
Peptides
Phenotype
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Tubulin

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