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Article

The effect of HFE mutations on serum ferritin and transferrin saturation in the Jersey population.

British journal of haematology - 1 May 1998

Merryweather-Clarke A T, Worwood M, Parkinson L, Mattock C, Pointon J J, Shearman J D, Robson K J

Abstract excerpt

High frequencies of the haemochromatosis-related HFE C282Y mutation have been reported in North European populations, in which a high proportion of patients with the disease are homozygotes. However, the degree of penetrance of this genotype is unknown. We determined the HFE C282Y and H63D genoty...

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Mutation
Genotype
Homozygote
Transferrin
Hemochromatosis
Ferritins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9609537
DOI: 10.1046/j.1365-2141.1998.00736.x

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9609537-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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The effect of HFE mutations on serum ferritin and transferrin saturation in the Jersey population.PMID 9609537Read ↗

Haematological effects of the C282Y HFE mutation in homozygous and heterozygous states among subjects of northern and southern European ancestry.Semantic proximity Read ↗

Nonexpressing homozygotes for C282Y hemochromatosis: minority or majority of cases?Semantic proximity Read ↗

Genetic screening for HFE hemochromatosis in 6,020 Danish men: penetrance of C282Y, H63D, and S65C variants.Semantic proximity Read ↗

Haemochromatosis mutations in North-East Scotland.Semantic proximity Read ↗

Prevalence of C282Y and H63D mutations in the hemochromatosis (HFE) gene in the United States.Semantic proximity Read ↗

HFE genotype and parameters of iron metabolism in German first-time blood donors - evidence for an increased transferrin saturation in C282Y heterozygotes.Semantic proximity Read ↗

Hemochromatosis gene HFE Cys282Tyr mutation analysis in a cohort of Northeast German hospitalized patients supports assumption of a North to South allele frequency gradient throughout Germany.Semantic proximity Read ↗

Prevalence and penetrance of HFE mutations in 4865 unselected primary care patients.Semantic proximity Read ↗

The significance of haemochromatosis gene mutations in the general population: implications for screening.Semantic proximity Read ↗

HFE mutations, iron deficiency and overload in 10,500 blood donors.Semantic proximity Read ↗

Screening for C282Y homozygosity in a Norwegian population (HUNT2): The sensitivity and specificity of transferrin saturation.Semantic proximity Read ↗

High prevalence of the hemochromatosis-associated Cys282Tyr HFE gene mutation in a healthy Norwegian population in the city of Oslo, and its phenotypic expression.Semantic proximity Read ↗

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