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Article

Screening for C282Y homozygosity in a Norwegian population (HUNT2): The sensitivity and specificity of transferrin saturation.

Scandinavian journal of clinical and laboratory investigation - 1 Apr 2010

Thorstensen Ketil, Kvitland Mona A, Irgens Wenche Ø, Hveem Kristian, Asberg Arne

Abstract excerpt

OBJECTIVE: Hereditary hemochromatosis (HH) is a genetic condition characterized by increased iron absorption. Most HH cases are homozygous for the C282Y mutation in the HFE gene, but accurate prevalence data for the Norwegian population is lacking. In population studies, serum transferrin saturation (TS) is commonly used as a screening test. However, the sensitivity and specificity of TS in this setting is not...

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Identifiers

PMID: 20073670
DOI: 10.3109/00365510903527838

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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