Article
The deletion polymorphism of the angiotensin-converting enzyme is associated with nephroangiosclerosis.
American journal of hypertension - 1 Apr 2000
Mallamaci F, Zuccalà A, Zoccali C, Testa A, Gaggi R, Spoto B, Martorano C, Curatola A, Misefari V, Cuzzola F, Romeo G, Zucchelli P
Abstract excerpt
The D allele of the angiotensin-converting enzyme (ACE) gene has been linked with diabetic nephropathy and IgA glomerulonephritis and with faster renal disease progression. The association of this allele with nephroangiosclerosis has been scarcely investigated. We have tested this association in 45 hypertensive patients (all whites) with well defined nephroangiosclerosis (diagnosis established on the basis of...
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