Article
The relative power of linkage and association studies for the detection of genes involved in hypertension.
Kidney international - 1 Jun 1998
Jones H B
Abstract excerpt
Hypertension is a common disorder that shows a polygenic mode of inheritance. Attempts to localize genes involved in the disorder have been carried out using both linkage and association tests. The relative merit of these two approaches is reviewed with an assessment of their utility for detecting genes involved in hypertension. Power calculations were carried out following the method of Risch and Merikangas [1],...
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