Article
Role of the multidrug efflux systems of Pseudomonas aeruginosa in organic solvent tolerance.
Journal of bacteriology - 1 Jun 1998
Li X Z, Zhang L, Poole K
Abstract excerpt
Multidrug efflux pumps with a broad substrate specificity make a major contribution to intrinsic and acquired multiple antibiotic resistance in Pseudomonas aeruginosa. Using genetically defined efflux pump mutants, we investigated the involvement of the three known efflux systems, MexA-MexB-OprM, MexC-MexD-OprJ, and MexE-MexF-OprN, in organic solvent tolerance in this organism. Our results showed that all three...
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