Article
Role of the multidrug efflux systems of Pseudomonas aeruginosa in organic solvent tolerance.
Journal of bacteriology - 1 Jun 1998
Li X Z, Zhang L, Poole K
Abstract excerpt
Multidrug efflux pumps with a broad substrate specificity make a major contribution to intrinsic and acquired multiple antibiotic resistance in Pseudomonas aeruginosa. Using genetically defined efflux pump mutants, we investigated the involvement of the three known efflux systems, MexA-MexB-OprM,...
Topics
- Bacterial Outer Membrane Proteins
- Carbonyl Cyanide m-Chlorophenyl Hydrazone
- Drug Resistance, Microbial
- Drug Resistance, Multiple
- Hydrocarbons
- Ionophores
- Mutation
- Pseudomonas aeruginosa
- Solvents
