Article
Identification and molecular characterization of an efflux system involved in Pseudomonas putida S12 multidrug resistance.
Microbiology (Reading, England) - 1 Jan 2001
Kieboom J, de Bont J
Abstract excerpt
The authors previously described srpABC, an operon involved in proton-dependent solvent efflux in the solvent-tolerant Pseudomonas putida S12. Recently, it was shown that organic solvents and not antibiotics induce this operon. In the present study, the authors characterize a new efflux pump, designated ArpABC, on the basis of two isolated chloramphenicol-sensitive transposon mutants. The arpABC operon is...
Topics
- Amino Acid Sequence
- Anti-Bacterial Agents
- Bacterial Proteins
- Base Sequence
- Benzene Derivatives
- Carrier Proteins
- Chloramphenicol
- Chloramphenicol Resistance
- DNA Transposable Elements
- Drug Resistance, Microbial
- Drug Resistance, Multiple
- Genetic Complementation Test
- Membrane Transport Proteins
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Pseudomonas putida