Article
Postreassortment changes in influenza A virus hemagglutinin restoring HA-NA functional match.
Virology - 10 May 1998
Kaverin N V, Gambaryan A S, Bovin N V, Rudneva I A, Shilov A A, Khodova O M, Varich N L, Sinitsin B V, Makarova N V, Kropotkina E A
Abstract excerpt
An important function of influenza virus neuraminidase (NA) is the removal of sialic acid residues from virion components in order to prevent the aggregation of virus particles. In previous communications we have reported that reassortant viruses containing the NA gene of A/USSR/90/77 (H1N1) virus and HA genes of H3, H4, H10, or H13 subtypes had a tendency to virion aggregation at 4 degrees C and that the virion...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
