Article
Postreassortment changes in influenza A virus hemagglutinin restoring HA-NA functional match.
Virology - 10 May 1998
Kaverin N V, Gambaryan A S, Bovin N V, Rudneva I A, Shilov A A, Khodova O M, Varich N L, Sinitsin B V, Makarova N V, Kropotkina E A
Abstract excerpt
An important function of influenza virus neuraminidase (NA) is the removal of sialic acid residues from virion components in order to prevent the aggregation of virus particles. In previous communications we have reported that reassortant viruses containing the NA gene of A/USSR/90/77 (H1N1) viru...
Topics
- Amino Acid Substitution
- Animals
- Cell Membrane
- Chick Embryo
- Genetic Variation
- HN Protein
- Hemagglutinin Glycoproteins, Influenza Virus
- Influenza A virus
- Neuraminidase
- Point Mutation
- Receptors, Virus
- Sialic Acids
- Viral Proteins