Enhanced macrophage uptake of lipoprotein(a) after Ca2+-induced aggregate-formation.

doi:10.1007/s11745-998-0219-5

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Article

Enhanced macrophage uptake of lipoprotein(a) after Ca2+-induced aggregate-formation.

Lipids - 1 Apr 1998

Tanaka S, Yashiro A, Tasaki H, Nakashima Y

Abstract excerpt

We tested the hypothesis that aggregated lipoprotein(a) [Lp(a)] is avidly taken up by macrophages. Lp(a) was isolated by sequential centrifugations and gel chromatography from a patient with high plasma levels of Lp(a) who was being treated with low density lipoprotein (LDL)-apheresis. Aggregated...

Topics

Aged
Animals
Calcium
Cholesterol
Cholesterol Esters
Cytochalasin B
Dose-Response Relationship, Drug
Esterification
Female
Humans
Lipoprotein(a)
Macrophages
Male
Mice
Phenotype
Protein Binding

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