Apolipoprotein E and lipoprotein lipase secreted from human monocyte-derived macrophages modulate very low density lipoprotein uptake.

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Article

Apolipoprotein E and lipoprotein lipase secreted from human monocyte-derived macrophages modulate very low density lipoprotein uptake.

The Journal of biological chemistry - 25 Feb 1990

Ishibashi S, Yamada N, Shimano H, Mori N, Mokuno H, Gotohda T, Kawakami M, Murase T, Takaku F

Abstract excerpt

We investigated the roles of lipoprotein lipase and apolipoprotein E (apoE) secreted from human monocyte-derived macrophages in the uptake of very low density lipoproteins (VLDL). ApoCII-deficient VLDL were isolated from a patient with apoCII deficiency. The lipolytic conversion to higher density and the degradation of the apoCII-deficient VLDL by macrophages were very slight, whereas the addition of apoCII...

Topics

Apolipoprotein C-II
Apolipoproteins C
Apolipoproteins E
Biological Transport
Cells, Cultured
Female
Fibroblasts
Humans
Hyperlipoproteinemia Type III
Infant
Kinetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipoprotein Lipase

Lipoproteins

Lipoproteins, VLDL

Macrophages

Male

Middle Aged

Monocytes

Source

Open in PubMed

Identifiers

PMID: 2303437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2303437-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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