Article
The molecular basis of nephrogenic diabetes insipidus.
Journal of molecular medicine (Berlin, Germany) - 1 Apr 1998
Oksche A, Rosenthal W
Abstract excerpt
Nephrogenic diabetes insipidus (NDI) is characterized by resistance of the kidney to the action of arginine-vasopressin (AVP); it may be due to genetic or acquired causes. Recent advances in molecular genetics have allowed the identification of the genes involved in congenital NDI. While inactivating mutations of the vasopressin V2 receptor are responsible for X-linked NDI, autosomal recessive NDI is caused by...
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