Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Polymorphism and Natural Selection in the Malaria Parasite Plasmodium falciparum

1 May 1998

Abstract excerpt

We have studied the genetic polymorphism at 10 Plasmodium falciparum loci that are considered potential targets for specific antimalarial vaccines. The polymorphism is unevenly distributed among the loci; loci encoding proteins expressed on the surface of the sporozoite or the merozoite (AMA-1, CSP, LSA-1, MSP-1, MSP-2, and MSP-3) are more polymorphic than those expressed during the sexual stages or inside the...

Source

Identifiers

PMID: 9584096
DOI: 10.1093/genetics/149.1.189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Polymorphism and Natural Selection in the Malaria Parasite Plasmodium falciparumPMID 9584096Read ↗

Polymorphism in the gene encoding the Pfs48/45 antigen of Plasmodium falciparum. XI. Asembo Bay Cohort Project.Semantic proximity Read ↗

Contrasting population structures of the genes encoding ten leading vaccine-candidate antigens of the human malaria parasite, Plasmodium falciparum.Semantic proximity Read ↗

Genetic diversity of three surface protein genes in Plasmodium malariae from three Asian countries.Semantic proximity Read ↗

Prospective identification of malaria parasite genes under balancing selection.Semantic proximity Read ↗

Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum.Semantic proximity Read ↗

Strong diversifying selection on domains of the Plasmodium falciparum apical membrane antigen 1 gene.Semantic proximity Read ↗

Global diversity and balancing selection of 23 leading Plasmodium falciparum candidate vaccine antigensSemantic proximity Read ↗

Genetic variation and the recent worldwide expansion of Plasmodium falciparum.Semantic proximity Read ↗

Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome.Semantic proximity Read ↗

A comparative study of the genetic diversity of the 42kDa fragment of the merozoite surface protein 1 in Plasmodium falciparum and P. vivax.Semantic proximity Read ↗

Genome-Wide Patterns of Genetic Polymorphism and Signatures of Selection in Plasmodium vivaxSemantic proximity Read ↗

The evolution and diversity of a low complexity vaccine candidate, merozoite surface protein 9 (MSP-9), in Plasmodium vivax and closely related species.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.