Article
Diabetes mellitus and cardiomyopathy--association with mutation in the mitochondrial tRNA(Leu)(UUR) gene.
Japanese circulation journal - 1 Apr 1998
Shiotani H, Ueno H, Inoue S, Yokota Y, Yokoyama M
Abstract excerpt
In this report, cardiac abnormalities in 2 diabetic patients with a mutation in the mitochondrial tRNA(Leu)(UUR)gene are described. The 2 patients exhibited left ventricular dilation and diffuse decreased wall motion. Cardiac catheterization studies revealed normal coronary angiography. In both patients, light microscopic examination of hematoxylin and eosin-stained sections revealed myocyte hypertrophy and...
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