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Article

The relationship between phenytoin pharmacokinetics and the CYP2C19 genotype in Japanese epileptic patients.

Clinical neuropharmacology - 1 Jan 2000

Watanabe M, Iwahashi K, Kugoh T, Suwaki H

Abstract excerpt

The relationship between the phenytoin pharmacokinetics, expressed by the mean of the Michaelis-Menten equation and the CYP2C19 genotype was investigated in 16 Japanese epileptic patients treated with phenytoin. Between genetically (S)-mephenytoin poor and extensive metabolizers, there were no di...

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PMID: 9579299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9579299-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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