Article
Spontaneous transdifferentiation of quail pigmented epithelial cell is accompanied by a mutation in the Mitf gene.
Developmental biology - 15 Apr 1998
Mochii M, Ono T, Matsubara Y, Eguchi G
Abstract excerpt
An ectopic neural retina is formed at the outer layer of the retina in the silver homozygote (B/B) of the Japanese quail. In situ hybridization and immunohistochemical analysis revealed that cells in the outer layer of retina first expressed a pigment-cell-specific gene, mmp115, and then began to...
Topics
- Amino Acid Sequence
- Animals
- Avian Proteins
- Base Sequence
- Cell Differentiation
- Cell Division
- Cell Nucleus
- Cells, Cultured
- Cloning, Molecular
- Coturnix
- DNA-Binding Proteins
- Gene Expression Regulation, Developmental
- Heterozygote
- Homozygote
- L Cells
- Lens, Crystalline
- Mice
- Microphthalmia-Associated Transcription Factor