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Article

Alternative promoter use in eye development: the complex role and regulation of the transcription factor MITF.

Development (Cambridge, England) - 1 Mar 2008

Bharti Kapil, Liu Wenfang, Csermely Tamas, Bertuzzi Stefano, Arnheiter Heinz

Abstract excerpt

During vertebrate eye development, the transcription factor MITF plays central roles in neuroepithelial domain specification and differentiation of the retinal pigment epithelium. MITF is not a single protein but represents a family of isoforms generated from a common gene by alternative promoter/exon use. To address the question of the role and regulation of these isoforms, we first determined their expression...

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Source

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Identifiers

PMID: 18272592
DOI: 10.1242/dev.014142
PMCID: PMC2276638

Genes

MITF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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