Frequency of the 20210 G-->A mutation in the 3'-untranslated region of the prothrombin gene in 35 cases of cerebral venous thrombosis.

doi:10.1161/01.str.29.7.1398

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Article

Frequency of the 20210 G-->A mutation in the 3'-untranslated region of the prothrombin gene in 35 cases of cerebral venous thrombosis.

Stroke - 1 Jul 1998

Biousse V, Conard J, Brouzes C, Horellou M H, Ameri A, Bousser M G

Abstract excerpt

BACKGROUND AND PURPOSE: A novel sequence variation in the 3'-untranslated region of the prothrombin (factor II) gene (nucleotide 20210 G-->A) has been recently described as a risk factor for deep vein thrombosis and pulmonary embolism. It is found in approximately 1% to 4% of healthy subjects. We...

Topics

Adolescent
Adult
Aged
Alleles
Base Sequence
Cerebral Veins
Child
Female
Humans
Male
Middle Aged
Mutation
Polymorphism, Genetic
Prothrombin
Risk Factors
Thrombophlebitis

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