Association of apolipoprotein E epsilon2 and vasculopathy in cerebral amyloid angiopathy.

doi:10.1212/wnl.50.4.961

Back to search

Article

Association of apolipoprotein E epsilon2 and vasculopathy in cerebral amyloid angiopathy.

Neurology - 1 Apr 1998

Greenberg S M, Vonsattel J P, Segal A Z, Chiu R I, Clatworthy A E, Liao A, Hyman B T, Rebeck G W

Abstract excerpt

OBJECTIVE: Hemorrhage related to cerebral amyloid angiopathy (CAA) appears to occur through a multistep pathway that includes deposition of beta-amyloid in cerebral vessels and specific vasculopathic changes in the amyloid-laden vessels, such as cracking of the vessel wall. Recent reports suggest...

Topics

Age Factors
Aged
Aged, 80 and over
Amyloidosis
Apolipoprotein E2
Apolipoproteins E
Cerebral Arteries
Cerebral Hemorrhage
Cohort Studies
Genotype
Humans
Middle Aged

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.