APOE gene polymorphism as a risk factor for cerebral amyloid angiopathy-related hemorrhage.

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Article

APOE gene polymorphism as a risk factor for cerebral amyloid angiopathy-related hemorrhage.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Jul 2001

Nicoll J A, McCarron M O

Abstract excerpt

Cerebral amyloid angiopathy (CAA) due to the accumulation of amyloid beta-protein (Abeta) occurs in up to half of elderly individuals and in most cases of Alzheimer's disease (AD). Following identification of the apolipoprotein E (APOE) epsilon4 allele as a risk factor for AD, APOE epsilon4 was also found to be associated with asymptomatic CAA. The major clinical manifestation of CAA is stroke due to a lobar...

Topics

Alzheimer Disease
Apolipoprotein E2
Apolipoprotein E4
Apolipoproteins E
Cerebral Amyloid Angiopathy
Cerebral Hemorrhage
Genotype
Humans
Polymorphism, Genetic
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 11676291

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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