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Article

Identification of novel genes and pathways affecting Salmonella type III secretion system 1 using a contact-dependent hemolysis assay.

Journal of bacteriology - 1 May 2008

Field Terry R, Layton Abigail N, Bispham Jennie, Stevens Mark P, Galyov Edouard E

Abstract excerpt

We screened 5,700 Salmonella enterica serovar Typhimurium mutants for defects in type III secretion system 1 (T3SS-1)-mediated contact-dependent hemolysis to identify novel genes and pathways affecting the activity of T3SS-1. Our data suggest that previously unrecognized factors such as type I fimbriae may modulate the expression, activity, or deployment of this key virulence factor.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18310344
DOI: 10.1128/JB.01189-07
PMCID: PMC2347372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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