Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid.

doi:10.1038/ng1470

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Article

Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid.

Nature genetics - 1 Dec 2004

McClelland Michael, Sanderson Kenneth E, Clifton Sandra W, Latreille Phil, Porwollik Steffen, Sabo Aniko, Meyer Rekha, Bieri Tamberlyn, Ozersky Phil, McLellan Michael, Harkins C Richard, Wang Chunyan, Nguyen Christine, Berghoff Amy, Elliott Glendoria, Kohlberg Sara, Strong Cindy, Du Feiyu, Carter Jason, Kremizki Colin, Layman Dan, Leonard Shawn, Sun Hui, Fulton Lucinda, Nash William, Miner Tracie, Minx Patrick, Delehaunty Kim, Fronick Catrina, Magrini Vincent, Nhan Michael, Warren Wesley, Florea Liliana, Spieth John, Wilson Richard K

Abstract excerpt

Salmonella enterica serovars often have a broad host range, and some cause both gastrointestinal and systemic disease. But the serovars Paratyphi A and Typhi are restricted to humans and cause only systemic disease. It has been estimated that Typhi arose in the last few thousand years. The sequence and microarray analysis of the Paratyphi A genome indicates that it is similar to the Typhi genome but suggests that...

Topics

Base Sequence
Evolution, Molecular
Gene Library
Genetic Variation
Genome Components
Genome, Bacterial
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microarray Analysis

Molecular Sequence Data

Mutation

Pseudogenes

Salmonella paratyphi A

Salmonella typhi

Sequence Analysis, DNA

Species Specificity

Source

Open in PubMed

Identifiers

PMID: 15531882
DOI: 10.1038/ng1470

Provenance

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