Article
Phenotypical heterogeneity of CD4+CD8+ double-positive chronic T lymphoid leukemia.
Leukemia - 1 Apr 1998
Mizuki M, Tagawa S, Machii T, Shibano M, Tatsumi E, Tsubaki K, Tako H, Yokohama A, Satou S, Nojima J, Hirota T, Kitani T
Abstract excerpt
Chronic T lymphoid leukemias are defined as leukemias of post-thymic T cells. The CD4+CD8+ double-positive (DP) phenotype is seen in a few cases. Since DP generally occurs in thymic T cells, whether the DP T leukemia cells represent thymic or peripheral T cells has been a matter of controversy. T...
Topics
- Adult
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Humans
- Immunophenotyping
- Interleukin-4
- Leukemia, Prolymphocytic, T-Cell
- Lymphocyte Activation
- Phenotype