Expression of CD8beta and alteration of cell surface phenotype in adult T-cell leukaemia cells.

doi:10.1046/j.1365-2141.1997.1853002.x

Back to search

Article

Expression of CD8beta and alteration of cell surface phenotype in adult T-cell leukaemia cells.

British journal of haematology - 1 Jul 1997

Joh T, Yamada Y, Seto M, Kamihira S, Tomonaga M

Abstract excerpt

Typical adult T-cell leukaemia (ATL) cells have a CD4+ CD8- cell surface phenotype, but atypical phenotypes such as CD4+ CD8+ and CD4- CD8+ have also been reported. The CD8 molecule is composed of alpha and beta chains and commonly used monoclonal antibodies against CD8 molecule detect only CD8al...

Topics

Adult
Blotting, Southern
CD4 Antigens
CD8 Antigens
Female
Flow Cytometry
Humans
Leukemia, T-Cell
Phenotype
Tumor Cells, Cultured

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.