Article
Diversity of leukaemic cell morphology in ATL correlates with prognostic factors, aberrant immunophenotype and defective HTLV-1 genotype.
British journal of haematology - 1 May 1999
Tsukasaki K, Imaizumi Y, Tawara M, Fujimoto T, Fukushima T, Hata T, Maeda T, Yamada Y, Kamihira S, Tomonaga M
Abstract excerpt
To investigate the diversity of morphology in adult T-cell leukaemia/lymphoma (ATL) and its possible association with the pathophysiology of ATL, we selected 36 acute cases and 14 chronic cases phenotypically confirmed to have >90% ATL cells in peripheral blood mononuclear cells. Prototype ATL cells were observed in all cases, although the percentage of all lymphoid cells varied considerably (48.9 +/- 23.8 in...
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