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Article

Large granular lymphocytic leukaemia with a mixed T-cell/B-cell phenotype.

British journal of haematology - 1 Feb 1998

Akashi K, Shibuya T, Nakamura M, Oogami A, Harada M, Niho Y

Abstract excerpt

We report a case of large granular lymphocytic leukaemia (LGLL) with mixed T-cell/B-cell phenotypes. The LGLL cells expressed T-cell markers such as CD1, CD2, CD3, CD5, CD7, CD8 and CD57. The CD8+ LGLL cells coexpressed B-cell markers including CD20 and PCA-1, and a fraction of purified CD8+ LGLL cells secreted double isotypes of immunoglobulins (IgG-kappa and IgA-kappa). Both TCRB and IGH genes were clonally...

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Source

Identifiers

PMID: 9488615
DOI: 10.1046/j.1365-2141.1998.00552.x

Genes

IGH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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