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Article

Mecamylamine selectively blocks nicotinic receptors on vasomotor sympathetic C neurons.

Brain research - 30 Mar 1998

Shen W X, Horn J P

Abstract excerpt

Mecamylamine differentially blocked fast nicotinic transmission in two functional subsets of sympathetic neurons within lumbar paravertebral ganglia of the bullfrog. EC50s for inhibition of postsynaptic compound action potentials were 27.3+/-2.5 microM in the secretomotor B system and 5.7+/-0.7 microM in the vasomotor C system. This 5.2:1 selectivity is 2.6 times greater than observed previously with...

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PMID: 9554976
DOI: 10.1016/s0006-8993(97)01520-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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