Article
[Determination of acetylator phenotype of isoniazid by superimposed sinusodial tension polarography].
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie - 1 Jan 2000
Vallon J J, Badinand A, Bichon C
Abstract excerpt
Alternative current polarography has been applied to specific determination of INH and acetyl-isoniazide in serum and urine. Determinations can be achieved directly on diluted urines. The method allows measure of pharmacocinetic parameters and determination of acetylation phenotype following I.V. administration of the drug.
Topics
- Acetylation
- Colorimetry
- Humans
- Hydrazines
- Isoniazid
- Methods
- Oxidation-Reduction
- Phenotype
- Polarography
