Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sunlight and carcinogenesis: Expression ofp53 and pyrimidine dimers in human skin following UVA I, UVA I + II and solar simulating radiations

13 Apr 1998

Abstract excerpt

DNA damage by UV radiation plays an essential role in skin cancer induction. We report that even sub-erythemal doses of solar simulating radiation, are capable of inducing substantial nuclear damage, namely pyrimidine dimers and p53 induction in human skin in situ. The quantity and distribution of p53 induced in human skin by UV radiation depended highly on the waveband and dose of UV used. Solar simulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms
Share to Skin Protection and Aging

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9537581
DOI: 10.1002/(sici)1097-0215(19980413)76:2<201::aid-ijc6>3.0.co;2-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sunlight and carcinogenesis: Expression ofp53 and pyrimidine dimers in human skin following UVA I, UVA I + II and solar simulating radiationsPMID 9537581Read ↗

Characterization of a Human Skin Equivalent Model to Study the Effects of Ultraviolet B Radiation on KeratinocytesSemantic proximity Read ↗

Protection Against Pyrimidine Dimers, p53, and 8-hydroxy-2′-Deoxyguanosine Expression in Ultraviolet-Irradiated Human Skin by Sunscreens: Difference Between UVB + UVA and UVB Alone SunscreensSemantic proximity Read ↗

Dose and time effects of solar‐simulated ultraviolet radiation on the <i>in vivo</i> human skin transcriptomeSemantic proximity Read ↗

In Situ Repair of Cyclobutane Pyrimidine Dimers and 6–4 Photoproducts in Human Skin Exposed to Solar Simulating RadiationSemantic proximity Read ↗

Cyclobutane pyrimidine dimer formation and p53 production in human skin after repeated UV irradiationSemantic proximity Read ↗

Individual and combined effects of the infrared, visible, and ultraviolet light components of solar radiation on damage biomarkers in human skin cellsSemantic proximity Read ↗

Ultraviolet A within sunlight induces mutations in the epidermal basal layer of engineered human skin.Semantic proximity Read ↗

Cumulative effects from repeated exposures to suberythemal doses of UVB and UVA in human skinSemantic proximity Read ↗

Dark cyclobutane pyrimidine dimers are formed in the epidermis of Fitzpatrick skin types I/II and VI in vivo after exposure to solar‐simulated radiationSemantic proximity Read ↗

Short- and long-wave UV light (UVB and UVA) induce similar mutations in human skin cells.Semantic proximity Read ↗

Accumulated p53 protein and UVA protection level of sunscreensSemantic proximity Read ↗

Induction of oxidative DNA base damage in human skin cells by UV and near visible radiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.