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Article

Dose and time effects of solar‐simulated ultraviolet radiation on the <i>in vivo</i> human skin transcriptome

17 Sept 2019

Abstract excerpt

BACKGROUND: Terrestrial ultraviolet (UV) radiation causes erythema, oxidative stress, DNA mutations and skin cancer. Skin can adapt to these adverse effects by DNA repair, apoptosis, keratinization and tanning. OBJECTIVES: To investigate the transcriptional response to fluorescent solar-simulated radiation (FSSR) in sun-sensitive human skin in vivo. METHODS: Seven healthy male volunteers were exposed to 0, 3 and...

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PMID: 31529490
DOI: 10.1111/bjd.18527

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