Article
Ultraviolet A within sunlight induces mutations in the epidermal basal layer of engineered human skin.
The American journal of pathology - 1 Apr 2009
Huang Xiao Xuan, Bernerd Françoise, Halliday Gary Mark
Abstract excerpt
The ultraviolet B (UVB) waveband within sunlight is an important carcinogen; however, UVA is also likely to be involved. By ascribing mutations to being either UVB or UVA induced, we have previously shown that human skin cancers contain similar numbers of UVB- and UVA-induced mutations, and, importantly, the UVA mutations were at the base of the epidermis of the tumors. To determine whether these mutations...
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