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Article

Folding and cell surface expression of the vasopressin V2 receptor: requirement of the intracellular C-terminus.

FEBS letters - 6 Mar 1998

Oksche A, Dehe M, Schülein R, Wiesner B, Rosenthal W

Abstract excerpt

We characterized truncations of the human vasopressin V2 receptor to determine the role of the intracellular C-terminus (comprising about 44 amino acids) in receptor function and cell surface expression. In contrast to the wild-type receptor, the naturally occurring mutant R337X failed to confer specific [3H]AVP binding to transfected cells. In addition, no vasopressin-sensitive adenylyl cyclase was detectable in...

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Identifiers

PMID: 9537515
DOI: 10.1016/s0014-5793(98)00140-9

Genes

AVP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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